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Scientific research background
64+ Peer-Reviewed Citations

Medical Sources

Every claim Pureami Tea Company makes is grounded in published, peer-reviewed medical literature. Below are the sources — all available free at PubMed.com.

Our Commitment to Transparency

The three names — Myricetin, DiHydroMyricetin, and Ampelopsin — all refer to the same flavonol. Search any of them on PubMed.com and you will find a substantial body of evidence. Qing Yun Moyeam produces this compound at 30–40% by plant weight, versus 3–6% for ordinary grades.

We do not cherry-pick studies. We have never made a claim not supported by the published literature. All citations below link directly to their source on PubMed or the original journal.

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Scientific journal and tea

SH003 Blend

Astragalus membranaceus · Angelica gigas · Trichosanthes kirilowii

9 studies

Gastric Cancer

57.
SH003 activates autophagic cell death by activating ATF4 and inhibiting G9a under hypoxia in gastric cancer cells

PubMed

SH003 triggered a form of cancer cell self-destruction (autophagic cell death) in gastric cancer cells even under low-oxygen conditions that typically allow tumors to survive.

Cervical Cancer

58.
SH003-induced G1 phase cell cycle arrest induces apoptosis in HeLa cervical cancer cells

PubMed

SH003 halted cervical cancer cell division at a key checkpoint and triggered programmed cell death, demonstrating anti-cancer activity against cervical cancer.

Breast Cancer

59.
SH003 reverses drug resistance by blocking STAT3 signaling in breast cancer cells

PubMed

SH003 overcame chemotherapy resistance in breast cancer cells by blocking a signaling pathway (STAT3) that tumors use to evade treatment.

60.
SH003 enhances paclitaxel chemosensitivity in MCF-7/PAX breast cancer cells through inhibition of MDR1 activity

PubMed

SH003 made paclitaxel chemotherapy more effective in drug-resistant breast cancer cells by suppressing a protein that normally pumps the drug out of cancer cells.

63.
SH003 suppresses breast cancer growth by accumulating p62 in autolysosomes

PubMed

SH003 inhibited breast cancer tumor growth by disrupting the cancer cells' waste-disposal system, causing a buildup of proteins that triggered cell death.

65.
Herbal extract SH003 suppresses tumor growth and metastasis of MDA-MB-231 breast cancer cells by inhibiting STAT3-IL-6 signaling

PubMed

SH003 suppressed both primary tumor growth and the spread (metastasis) of an aggressive form of breast cancer by blocking a key inflammatory cancer-promoting signaling axis.

Triple Negative Breast Cancer

61.
Synergistic effect of SH003 and doxorubicin in triple-negative breast cancer

PubMed

When combined with the chemotherapy drug doxorubicin, SH003 produced a synergistic effect — meaning the combination was significantly more powerful than either treatment alone against triple-negative breast cancer.

62.
SH003 selectively induces p73-dependent apoptosis in triple-negative breast cancer cells

PubMed

SH003 selectively triggered programmed cell death specifically in triple-negative breast cancer cells — the most aggressive and treatment-resistant subtype — while sparing healthy cells.

Tumor Angiogenesis

64.
SH003 represses tumor angiogenesis by blocking VEGF binding to VEGFR2

PubMed

SH003 cut off the blood supply to tumors by preventing the growth factor (VEGF) that tumors use to create new blood vessels from binding to its receptor — effectively starving the tumor.

Additional Research

Disclaimer: The research cited above is provided for educational purposes only and reflects the findings of independent researchers. Pureami Tea Company does not claim that Moyeam diagnoses, treats, cures, or prevents any disease. These statements have not been evaluated by the FDA. Consult your healthcare provider before making any changes to your diet or supplement regimen.